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42: Yoo EA, Kim SD, Lee WM, Park HJ, Kim SK, Cho JY, Min W, Rhee MH. Evaluation
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45: Reuter J, Jocher A, Stump J, Grossjohann B, Franke G, Schempp CM.
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46: Kametani S, Oikawa T, Kojima-Yuasa A, Kennedy DO, Norikura T, Honzawa M,
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53: Prabjone R, Thong-Ngam D, Wisedopas N, Chatsuwan T, Patumraj S.
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54: Micera A, Lambiase A, Puxeddu I, Aloe L, Stampachiacchiere B, Levi-Schaffer
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56: Antonelli A, Lapucci G, Vigneti E, Bonini S, Aloe L. Human lung fibroblast
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57: Beppu H, Shimpo K, Chihara T, Tamai I, Nomoto-Yamaji S, Ozaki S, Ito S,
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58: Fernandes AR, Favoreto A, Cruz A, Aloe M, Penna C. [Cerebral aneurysm related
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59: Esua MF, Rauwald JW. Novel bioactive maloyl glucans from aloe vera gel:
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60: Hristova M, Aloe L. Metabolic syndrome--neurotrophic hypothesis. Med
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61: Stampachiacchiere B, Aloe L. Differential modulatory effect of NGF on MHC
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62: Bracci-Laudiero L, Aloe L, Caroleo MC, Buanne P, Costa N, Starace G,
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64: Caroleo MC, Costa N, Tirassa P, Aloe L. Nerve growth factor produced by
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66: Tortorolo L, Langer A, Polidori G, Vento G, Stampachiacchere B, Aloe L,
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67: Wynn RL. Aloe vera gel: update for dentistry. Gen Dent. 2005
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68: Marinova TT, Velikova KK, Petrov DB, Kutev NS, Stankulov IS, Chaldakov GN,
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69: Speranza G, Morelli CF, Tubaro A, Altinier G, Durì L, Manitto P. Aloeresin I,
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70: Fernandez M, Giuliani A, Pirondi S, D'Intino G, Giardino L, Aloe L,
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72: Chiaretti A, Genovese O, Aloe L, Antonelli A, Piastra M, Polidori G, Di Rocco
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73: Chiaretti A, Antonelli A, Piastra M, Genovese O, Polidori G, Aloe L.
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74: Fray TR, Watson AL, Croft JM, Baker CD, Bailey J, Sirel N, Tobias A, Markwell
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75: Aloe L, Iannitelli A, Triaca V. [Nerve growth factor and multiple sclerosis: 
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76: Bautista-Pérez R, Segura-Cobos D, Vázquez-Cruz B. In vitro antibradykinin
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77: Langmead L, Feakins RM, Goldthorpe S, Holt H, Tsironi E, De Silva A, Jewell
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78: Langmead L, Makins RJ, Rampton DS. Anti-inflammatory effects of aloe vera gel
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79: Duansak D, Somboonwong J, Patumraj S. Effects of Aloe vera on leukocyte
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80: Aloe L. Nerve growth factor, human skin ulcers and vascularization. Our
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81: Manni L, Lundeberg T, Fiorito S, Bonini S, Vigneti E, Aloe L. Nerve growth
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82: Penissi AB, Rudolph MI, Piezzi RS. Role of mast cells in gastrointestinal
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83: Micera A, Puxeddu I, Aloe L, Levi-Schaffer F. New insights on the involvement
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84: Roselli M, Guadagni F, Martini F, Spila A, Mariotti S, D'Alessandro R, Aloe
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88: Bonini S, Rasi G, Bracci-Laudiero ML, Procoli A, Aloe L. Nerve growth factor:
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89: Jain A, Basal E. Inhibition of Propionibacterium acnes-induced mediators of
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90: Romano C, Rubegni P, De Aloe G, Stanghellini E, D'Ascenzo G, Andreassi L,
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97: Manni L, Lundeberg T, Tirassa P, Aloe L. Role of cholecystokinin-8 in nerve
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98: Levi-Schaffer F, Micera A, Zamir E, Mechoulam H, Puxeddu I, Piliponsky AM,
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99: Aloe L. Nerve growth factor and neuroimmune responses: basic and clinical
observations. Arch Physiol Biochem. 2001 Oct;109(4):354-6. Review. PubMed PMID:
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100: Bracci-Laudiero L, Aloe L, Buanne P, Finn A, Stenfors C, Vigneti E,
Theodorsson E, Lundeberg T. NGF modulates CGRP synthesis in human B-lymphocytes: 
a possible anti-inflammatory action of NGF? J Neuroimmunol. 2002
Feb;123(1-2):58-65. PubMed PMID: 11880150.


101: Ferroni P, Di Filippo F, Martini F, Spila A, D'Alessandro T, Cavaliere F,
Anzà M, Garinei R, Aloe S, Carone MD, Gazzaniga PP, Guadagni F. Effects of
isolated limb perfusion with tumor necrosis factor-alpha on circulating levels of
proinflammatory cytokines. J Immunother. 2001 Jul-Aug;24(4):354-62. PubMed PMID: 
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102: Mantle D, Gok MA, Lennard TW. Adverse and beneficial effects of plant
extracts on skin and skin disorders. Adverse Drug React Toxicol Rev. 2001
Jun;20(2):89-103. Review. PubMed PMID: 11482001.


103: Micera A, Vigneti E, Pickholtz D, Reich R, Pappo O, Bonini S, Maquart FX,
Aloe L, Levi-Schaffer F. Nerve growth factor displays stimulatory effects on
human skin and lung fibroblasts, demonstrating a direct role for this factor in
tissue repair. Proc Natl Acad Sci U S A. 2001 May 22;98(11):6162-7. Epub 2001 May
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104: Moore TE. The M and M's of aloe vera--is it for dentistry? J Okla Dent
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105: Rubegni P, De Aloe G, Pianigiani E, Cherubini-Di Simplicio F, Fimiani M. Two
sporadic cases of idiopathic multiple minute digitate hyperkeratosis. Clin Exp
Dermatol. 2001 Jan;26(1):53-5. PubMed PMID: 11260181.


106: Caroleo MC, Costa N, Bracci-Laudiero L, Aloe L. Human monocyte/macrophages
activate by exposure to LPS overexpress NGF and NGF receptors. J Neuroimmunol.
2001 Feb 15;113(2):193-201. PubMed PMID: 11164902.


107: Tirassa P, Manni L, Stenfors C, Lundeberg T, Aloe L. RT-PCR ELISA method for
the analysis of neurotrophin mRNA expression in brain and peripheral tissues. J
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108: Arosio B, Gagliano N, Fusaro LM, Parmeggiani L, Tagliabue J, Galetti P, De
Castri D, Moscheni C, Annoni G. Aloe-Emodin quinone pretreatment reduces acute
liver injury induced by carbon tetrachloride. Pharmacol Toxicol. 2000
Nov;87(5):229-33. PubMed PMID: 11129503.


109: Lambiase A, Bonini S, Aloe L, Rama P, Bonini S. Anti-inflammatory and
healing properties of nerve growth factor in immune corneal ulcers with stromal
melting. Arch Ophthalmol. 2000 Oct;118(10):1446-9. PubMed PMID: 11030834.


110: Vogler BK, Ernst E. Aloe vera: a systematic review of its clinical
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111: Fiore M, Angelucci F, Alleva E, Branchi I, Probert L, Aloe L. Learning
performances, brain NGF distribution and NPY levels in transgenic mice expressing
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112: Graf J. Herbal anti-inflammatory agents for skin disease. Skin Therapy Lett.
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113: volik NA, Beloklitskaia GF, Stefanov AV, Makarenko. [Effect of biogenic
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114: Pozza M, Bettelli C, Aloe L, Giardino L, Calzà L. Further evidence for a
role of nitric oxide in experimental allergic encephalomyelitis: aminoguanidine
treatment modifies its clinical evolution. Brain Res. 2000 Feb 7;855(1):39-46.
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115: Aloe L, Properzi F, Probert L, Akassoglou K, Kassiotis G, Micera A, Fiore M.
Learning abilities, NGF and BDNF brain levels in two lines of TNF-alpha
transgenic mice, one characterized by neurological disorders, the other
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116: Simone MD, De Santis S, Vigneti E, Papa G, Amadori S, Aloe L. Nerve growth
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1999 Mar;17(1):1-10. Review. PubMed PMID: 10440888.


117: Aloe L, Simone MD, Properzi F. Nerve growth factor: a neurotrophin with
activity on cells of the immune system. Microsc Res Tech. 1999 May 15-Jun
1;45(4-5):285-91. Review. PubMed PMID: 10383121.


118: Chauhan O, Godhwani JL, Khanna NK, Pendse VK. Antiinflammatory activity of
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119: Bonini S, Lambiase A, Bonini S, Levi-Schaffer F, Aloe L. Nerve growth
factor: an important molecule in allergic inflammation and tissue remodelling.
Int Arch Allergy Immunol. 1999 Feb-Apr;118(2-4):159-62. Review. PubMed PMID:
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120: Aloe L, Fiore M, Probert L, Turrini P, Tirassa P. Overexpression of tumour
necrosis factor alpha in the brain of transgenic mice differentially alters nerve
growth factor levels and choline acetyltransferase activity. Cytokine. 1999
Jan;11(1):45-54. PubMed PMID: 10080878.


121: Robinson M. Medical therapy of inflammatory bowel disease for the 21st
century. Eur J Surg Suppl. 1998;(582):90-8. Review. PubMed PMID: 10029372.


122: Manni L, Aloe L. Role of IL-1 beta and TNF-alpha in the regulation of NGF in
experimentally induced arthritis in mice. Rheumatol Int. 1998;18(3):97-102.
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123: Benigni F, Sacco S, Aloe L, Ghezzi P. Intracerebroventricular injection of
anti-Fas activates the hypothalamus-pituitary-adrenal axis and induces peripheral
interleukin-6 and serum amyloid A in mice: comparison with other ligands of the
tumor necrosis factor/nerve growth factor receptor superfamily. Am J Pathol. 1998
Nov;153(5):1377-81. PubMed PMID: 9811328; PubMed Central PMCID: PMC1853388.


124: Solomon A, Aloe L, Pe'er J, Frucht-Pery J, Bonini S, Bonini S, Levi-Schaffer
F. Nerve growth factor is preformed in and activates human peripheral blood
eosinophils. J Allergy Clin Immunol. 1998 Sep;102(3):454-60. PubMed PMID:
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125: Manni L, Micera A, Pistillo L, Aloe L. Neonatal handling in EAE-susceptible 
rats alters NGF levels and mast cell distribution in the brain. Int J Dev
Neurosci. 1998 Feb;16(1):1-8. PubMed PMID: 9664217.


126: Lambiase A, Bonini S, Micera A, Rama P, Bonini S, Aloe L. Expression of
nerve growth factor receptors on the ocular surface in healthy subjects and
during manifestation of inflammatory diseases. Invest Ophthalmol Vis Sci. 1998
Jun;39(7):1272-5. PubMed PMID: 9620090.


127: Calzà L, Giardino L, Pozza M, Bettelli C, Micera A, Aloe L. Proliferation
and phenotype regulation in the subventricular zone during experimental allergic 
encephalomyelitis: in vivo evidence of a role for nerve growth factor. Proc Natl 
Acad Sci U S A. 1998 Mar 17;95(6):3209-14. PubMed PMID: 9501242; PubMed Central
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128: Fiore M, Alleva E, Probert L, Kollias G, Angelucci F, Aloe L. Exploratory
and displacement behavior in transgenic mice expressing high levels of brain
TNF-alpha. Physiol Behav. 1998 Feb 15;63(4):571-6. PubMed PMID: 9523900.


129: Aloe L, Moroni R, Angelucci F, Fiore M. Role of TNF-alpha but not NGF in
murine hyperalgesia induced by parasitic infection. Psychopharmacology (Berl).
1997 Dec;134(3):287-92. PubMed PMID: 9438678.


130: Lambiase A, Bonini S, Micera A, Tirassa P, Magrini L, Bonini S, Aloe L.
Increased plasma levels of substance P in vernal keratoconjunctivitis. Invest
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131: Lambiase A, Bracci-Laudiero L, Bonini S, Bonini S, Starace G, D'Elios MM, De
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and express high-affinity nerve growth factor receptors. J Allergy Clin Immunol. 
1997 Sep;100(3):408-14. PubMed PMID: 9314355.


132: Aloe L, Bracci-Laudiero L, Bonini S, Manni L. The expanding role of nerve
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133: Aloe L, Tuveri MA. Nerve growth factor and autoimmune rheumatic diseases.
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134: Calzà L, Giardino L, Pozza M, Micera A, Aloe L. Time-course changes of nerve
growth factor, corticotropin-releasing hormone, and nitric oxide synthase
isoforms and their possible role in the development of inflammatory response in
experimental allergic encephalomyelitis. Proc Natl Acad Sci U S A. 1997 Apr
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135: Vázquez B, Avila G, Segura D, Escalante B. Antiinflammatory activity of
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136: Falcini F, Matucci Cerinic M, Lombardi A, Generini S, Pignone A, Tirassa P, 
Ermini M, Lepore L, Partsch G, Aloe L. Increased circulating nerve growth factor 
is directly correlated with disease activity in juvenile chronic arthritis. Ann
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137: Falcini F, Cerinic MM, Ermini M, Generini S, Lombardi A, Pignone A, Leoncini
G, Tirassa P, Aloe L. Nerve growth factor circulating levels are increased in
Kawasaki disease: correlation with disease activity and reduced angiotensin
converting enzyme levels. J Rheumatol. 1996 Oct;23(10):1798-802. PubMed PMID:
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138: Bonini S, Lambiase A, Bonini S, Angelucci F, Magrini L, Manni L, Aloe L.
Circulating nerve growth factor levels are increased in humans with allergic
diseases and asthma. Proc Natl Acad Sci U S A. 1996 Oct 1;93(20):10955-60. PubMed
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139: Hutter JA, Salman M, Stavinoha WB, Satsangi N, Williams RF, Streeper RT,
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140: Bracci-Laudiero L, Lundeberg T, Stenfors C, Theodorsson E, Tirassa P, Aloe
L. Modification of lymphoid and brain nerve growth factor levels in systemic
lupus erythematosus mice. Neurosci Lett. 1996 Feb 2;204(1-2):13-6. PubMed PMID:
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141: De Simone R, Micera A, Tirassa P, Aloe L. mRNA for NGF and p75 in the
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142: Lambiase A, Bonini S, Bonini S, Micera A, Magrini L, Bracci-Laudiero L, Aloe
L. Increased plasma levels of nerve growth factor in vernal keratoconjunctivitis 
and relationship to conjunctival mast cells. Invest Ophthalmol Vis Sci. 1995
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143: Aloe L, Probert L, Kollias G, Micera A, Tirassa P. Effect of NGF antibodies 
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144: Davis RH, DiDonato JJ, Johnson RW, Stewart CB. Aloe vera, hydrocortisone,
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145: Leon A, Buriani A, Dal Toso R, Fabris M, Romanello S, Aloe L,
Levi-Montalcini R. Mast cells synthesize, store, and release nerve growth factor.
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146: Davis RH, Donato JJ, Hartman GM, Haas RC. Anti-inflammatory and wound
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147: Aloe L, Skaper SD, Leon A, Levi-Montalcini R. Nerve growth factor and
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148: Aloe L, Leon A, Levi-Montalcini R. A proposed autacoid mechanism controlling
mastocyte behaviour. Agents Actions. 1993;39 Spec No:C145-7. PubMed PMID:
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149: Laudiero LB, Aloe L, Levi-Montalcini R, Buttinelli C, Schilter D, Gillessen 
S, Otten U. Multiple sclerosis patients express increased levels of beta-nerve
growth factor in cerebrospinal fluid. Neurosci Lett. 1992 Nov 23;147(1):9-12.
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150: Fogleman RW, Chapdelaine JM, Carpenter RH, McAnalley BH. Toxicologic
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151: Davis RH, Stewart GJ, Bregman PJ. Aloe vera and the inflamed synovial pouch 
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152: Aloe L, Tuveri MA, Carcassi U, Levi-Montalcini R. Nerve growth factor in the
synovial fluid of patients with chronic arthritis. Arthritis Rheum. 1992
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153: Davis RH, Parker WL, Samson RT, Murdoch DP. Isolation of a stimulatory
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154: Davis RH, Parker WL, Samson RT, Murdoch DP. The isolation of an active
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155: Davis RH, Parker WL, Murdoch DP. Aloe vera as a biologically active vehicle 
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156: 't Hart LA, Nibbering PH, van den Barselaar MT, van Dijk H, van den Berg AJ,
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157: t'Hart LA, van den Berg AJ, Kuis L, van Dijk H, Labadie RP. An
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158: Davis RH, Rosenthal KY, Cesario LR, Rouw GA. Processed Aloe vera
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159: Davis RH, Leitner MG, Russo JM, Byrne ME. Anti-inflammatory activity of Aloe
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160: Saito H, Imanishi K, Okabe S. [Effects of aloe extracts, aloctin A, on
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161: Davis RH, Maro NP. Aloe vera and gibberellin. Anti-inflammatory activity in 
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162: Davis RH, Leitner MG, Russo JM. Topical anti-inflammatory activity of Aloe
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164: Davis RH, Agnew PS, Shapiro E. Antiarthritic activity of anthraquinones
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165: Yagi A, Hamada K, Mihashi K, Harada N, Nishioka I. Structure determination
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167: Spoerke DG, Ekins BR. Aloe vera--fact or quackery. Vet Hum Toxicol. 1980
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